? What should I do if I have a high risk exposure incident?
May 2003
Immediate action can reduce the risk of transmission:
- if eyes or mouth are exposed wash in running water
- skin punctures should be encouraged to bleed gently and the area washed with soap
- if broken skin has been in contact with body fluids wash thoroughly
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The incident should be reported to the occupational health department (or accident and emergency personnel if the department is closed), where a baseline serum can be collected.
PHLS guidelines recommend testing of all source patients for evidence of HCV infection. The investigation and follow-up of health care workers that have been occupationally exposed to hepatitis C is shown in Table 2.
Table 2 – The investigation and follow-up of health care workers exposed to hepatitis C
| Known hepatitis C infected source |
Source known not to be infected with hepatitis C |
Hepatitis C status of source unknown |
| |
|
|
- collect baseline serum for storage from health care worker
- collect serum/ EDTA for HCV RNA testing at 6 and 12 weeks
- collect serum for anti-HCV testing at 12 and 24 weeks
|
- collect baseline serum for storage from health care worker
- collect follow up serum if symptoms or signs of liver disease develop
|
- collect baseline serum for storage from health care worker
- designated doctor to perform risk assessment
High risk
- manage as known infected source
Low risk
- collect serum for anti-HCV testing at 24 weeks
|
Occupational Health departments should be able to advise on any additional precautions/ restrictions to practice that may be required whilst a health care worker is undergoing tests as above.
Anyone who becomes HCV RNA positive should have an early referral to a specialist with expertise in liver disease, as there is now some evidence that early treatment of acute hepatitis C may prevent chronic infection.
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